When assessing a 24-hour-old newborn, a pink papular rash with vesicles on the trunk is observed. What action is appropriate?

• A. Notify the healthcare provider immediately.
• B. Move the newborn to an isolation nursery.
• C. Document the finding as erythema toxicum.
• D. Obtain a culture from one of the vesicles.

Answer: (C)

Erythema toxicum neonatorum is a common, benign rash that appears in the first days of life. It typically shows pink papules with tiny vesicles or pustules on an erythematous base, often on the trunk and face, and it resolves on its own within about 1–2 weeks. Because this is a normal, self-limiting finding, the appropriate action is to document it as erythema toxicum and reassure the family, while continuing routine newborn care. There’s no need to notify the provider immediately, move the baby to isolation, or culture the vesicles. Cultures or further workup would be considered only if the infant showed signs of illness or the rash had an atypical, concerning appearance.